Found 7117 of ic50 data for polymerid = 1129,384,50000884,50002482 TargetAmine oxidase [flavin-containing] A(Mus musculus)
R.C. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
R.C. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00490nMAssay Description:Inhibition of human monoamine oxidase AMore data for this Ligand-Target Pair
3D Structure (crystal)TargetAmine oxidase [flavin-containing] A(Mus musculus)
R.C. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
R.C. Patel Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of MAO-B in baboon liver mitochondriaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of rat MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.389nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human full length recombinant MAO-A expressed in insect cells using kynuramine as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.661nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MAO-A (unknown origin) by multi-well spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Compound was tested in vitro for inhibition of rat brain mitochondrial monoamine oxidase A.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat liver mitochondria MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells using p-tyramine as substrate preincubated for 15 mins followed by substrate addition fo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat liver mitochondria MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound against Monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Monoamine oxidase A (MAO A) in rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using tyramine as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of bovine brain mitochondria MAO-A using serotonin substrate after 60 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of rat liver mitochondria MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
